pH Dependence of Chitosan Enzymolysis

Optimization and Characterization of Chitosan Enzymolysis by Pepsin

Pepsin was used to effectively degrade chitosan in order to make it more useful in biotechnological applications. The optimal conditions of enzymolysis were investigated on the basis of the response surface methodology (RSM). The structure of the degraded product was characterized by degree of depolymerization (DD), viscosity, molecular weight, FTIR, UV-VIS, SEM and polydispersity index analyse...

pH dependence of sphingosine aggregation.

Sphingosine and sphingosine 1-phosphate (S1P) are sphingolipid metabolites that act as signaling messengers to activate or inhibit multiple downstream targets to regulate cell growth, differentiation, and apoptosis. The amphiphilic nature of these compounds leads to aggregation above their critical micelle concentrations (CMCs), which may be important for understanding lysosomal glycosphingolip...

pH dependence of the inhibition of yeast glyoxalase 1 by prophyrins

pH dependence of corneal oxygen consumption.

PURPOSE To determine whether corneal acidosis, which occurs during contact lens wear, alters corneal O2 consumption (QO2) and if so, whether increased ion transport activity could contribute to altered QO2 during acidosis. METHODS PO2 was measured, using the phosphorescence quenching of Pd-meso-tetra-(4-carboxyphenyl) porphine, in an airtight chamber that held a trephined rabbit cornea. The r...

pH Dependence of gagCEST at 7T

INTRODUCTION: Osteoarthritis (OA) is one of the major debilitating joint diseases of the musculoskeletal system affecting a large population worldwide. The initiating event of OA is thought to be predominantly due to loss of proteoglycans (PG) from the tissue (1). Recently, it has been shown that chemical exchange saturation transfer (CEST) of labile –OH protons on glycosaminoglycans (GAG) with...